We have developed innovative solutions for optimizing the process of accurately quantifying proteins in complex biological matrices and other complex mixtures.

Service Description

Traditional target protein analysis is based on antibody techniques, which have limitations in throughput and specificity. However, multiple reaction monitoring (MRM) and parallel reaction monitoring (PRM) approaches1 are able to resolve these obstacles.

As the gold standard for targeted proteomics research based on MS platforms, MRM/PRM technology can quickly and accurately determine dozens of proteins simultaneously in complex biological samples and solve slow verification problems.

Targeted Proteomics

Project Workflow

[1] Method of the Year 2012. Nat Methods, 2013. 10(1).

References

How to order

Targeted Proteomics services are performed using nano-flow liquid chromatography and cutting-edge mass spectrometer (Q Exactive HF/HF-X and QTRAP 6500).

<ul><li>Customized LC method and PRM-acquisition MS method</li></ul>

Sample Preparation and Services

<ul><li>Summary includes all methods and data analysis</li><li>Reports provided in Excel or PDF format, RAW files available upon request</li></ul>

Quality Standard

<ul><li>Typical 8 weeks from sample QC acceptance to data report delivery</li></ul>

Turn Around Time

Mass Spectrometry Service Specification

<ul><li>Summary of target proteins</li><li>Data quality</li><li>Method demonstration</li></ul>

METHOD DEVELOPMENT

<ul><li>Quantitative information</li><li>Data normalizatio</li><li>Quantification of target peptide</li></ul>

SAMPLE QUANTIFICATION