SENTIS Comprehensive Hereditary Cancer Panel
For Research Use Only. Not for use in diagnostic procedures.
Introduction
BGI’s hereditary risk screening cancer panels target genes previously linked to a predisposition of cancer. Panel selection was based on expert curation of scientific literature and other high-quality resources, including formal medical guidelines.
Individuals with a family history of cancer may have an increased risk of cancer if they have inherited a cancer-causing mutation. Different gene mutations can cause diverse types of cancer. The BGI SENTISTM Hereditary Cancer Panel analyzes germline mutations across 79 genes associated with 24 types of hereditary cancer, including some of the most common cancer types, such as hereditary breast, ovarian, colorectal, prostate, and stomach cancer. Identification of cancer-causing mutations can help guide treatment and health management decisions or guide further testing of at-risk relatives.
Laboratory Workflow Solution
We
enable customer‘s end-to-end testing of various sample types with the following proven
products/platforms (RUO in US and Canada).
*The automation and sequencing instruments are supplied by Complete Genomics directly.
Advantages
Comprehensive
- Whole exome plus flanking intronic regions covered for all genes tested; one single assay that detects point mutations, deletions, insertions, duplications, rearrangements*.
*Alterations in methylation and complex genomic aberrations such as uniparental disomy, balanced translocation, inversions, ploidy changes, duplication and deletion of large DNA fragments and/or other rare alternations are not included. Also, there are some regions that cannot be fully covered, including exon15 of CHEK2 gene, and exon1 of STK11 gene.
Flexible
Choose from versatile testing options with multiple cancer-specific subpanels, including female hereditary cancer, male hereditary cancer, breast/ovarian cancer, colorectal cancer, and more.
Easy-to-use
Experience a streamlined sample-to-results workflow with our platform and automated on-premises NGS bioinformatics system, enabling effortless obtainment of insightful reports from samples.